Inspire Therapy Overview

Inspire therapy is a small, fully implanted system that senses breathing patterns and delivers mild stimulation to maintain multilevel airway patency during sleep. Upper airway stimulation technology provides a first of its kind alternative for those suffering from obstructive sleep apnea who are unable to use or get consistent benefit from CPAP.

The Inspire system consists of three implanted components including a small generator, breathing sensor lead, and stimulation lead, all controlled with the small handheld Inspire sleep remote.

Thoughtful patient selection, selective stimulation of targeted airway muscles, and optimal stimulation timing all play an important role in maintaining airway patency and improving patient outcomes.

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Getting It Right

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Right Patient

Inspire therapy is indicated for patients with the following characteristics: 22 years of age or older, have moderate to severe Obstructive Sleep Apnea (OSA) (AHI range from 15-65 with <25% central apneas), unable to use or get consistent benefit from CPAP, and free of complete concentric collapse at the palate. Inspire therapy has not been tested in people with BMI greater than 32.

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Right Stimulation

The Inspire stimulation lead is designed to gently conform to a variety of hypoglossal (XII) nerve types. Securing the stimulation lead to the optimal location on the XII nerve facilitates stable, consistent stimulation of targeted airway muscles.

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Right Time

Using a proprietary algorithm, Inspire therapy continuously monitors the patient’s breathing patterns and delivers mild hypoglossal nerve stimulation during inspiration, which is when the airway is most vulnerable to collapse.

The Inspire Procedure

For most patients, the Inspire system can be implanted during an outpatient procedure. Patients may experience some pain and swelling at incision sites but should be able to return to nonstrenuous activities after a few days. Approximately one month after implantation, patients return to their doctor’s office where personalized stimulation settings are established and patients are trained to use the handheld sleep remote.

Why Choose Inspire therapy

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Less invasive than conventional OSA surgeries and preserves the natural airway anatomy

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Designed to maintain airway patency at multiple levels of the airway

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Clinically proven to significantly reduce sleep apnea events and improve quality of life.

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