Inspire Medical Systems, Inc. to Report Second Quarter 2018 Financial Results August 7, 2018

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MINNEAPOLIS (July 17, 2018) – Inspire Medical Systems, Inc. (“Inspire”) (NYSE: INSP), a medical
technology company focused on the development and commercialization of innovative and minimally
invasive solutions for patients with obstructive sleep apnea, today announced that it will release financial
results for the second quarter 2018 after the close of trading on Tuesday, August 7, 2018. Inspire’s
management team will host a corresponding conference call beginning at 5:00 p.m. ET to discuss the
financial results and recent business developments.

Tuesday, August 7th @ 5:00pm Eastern Time:
Domestic: 888-208-1711
International: 323-794-2577
Conference ID: 2893271
Webcast: http://public.viavid.com/index.php?id=130375

To listen to a live webcast, please visit the Investors section of the Inspire website at:
www.inspiresleep.com. The webcast replay will be available on the Inspire website for two weeks
following the completion of the call.

About Inspire Medical Systems
Inspire is a medical technology company focused on the development and commercialization of
innovative and minimally invasive solutions for patients with obstructive sleep apnea. Inspire Medical
Systems’ proprietary Inspire therapy is the first and only FDA-approved neurostimulation technology that
provides a safe and effective treatment for moderate to severe obstructive sleep apnea. For additional
information about Inspire, please visit www.inspiresleep.com.

Investor and Media Contact:
Bob Yedid
LifeSci Advisors
bob@lifesciadvisors.com
646-597-6989